Antagonistic Functions of USAG-1 and RUNX2 during Tooth Development.
Supernumerary teeth and tooth agenesis are common morphological anomalies in humans.We previously obtained evidence that supernumerary maxillary incisors form as a result of the successive development of the rudimentary maxillary incisor tooth germ in Usag-1 null mice.The development of Sports Bra tooth germs is arrested in Runx2 null mice, and suc